Title: Oral composition for improving oral health

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Claims: What is claimed is:

1. A therapeutic composition for topical oral administration for stimulating production of collagen consisting essentially of about 0.5 to about 2.0 percent by weight/volume of a pharmaceutically acceptable, water soluble zinc salt and about 0.5 to about 2.0 percent by weight/volume of ascorbic acid or sodium ascorbate.

2. The composition according to claim 1 wherein the ratio of the zinc salt to the ascorbic acid or sodium ascorbate is substantially 1 to 1 by weight.

3. The composition according ing to claim 2 wherein the zinc salt is ZnSO.sub.4.7H.sub.2 O.

4. The composition according to claim 3 wherein the pH is from about 4 to about 5.

5. A method for treating oral tissues by stimulating the production of collagen comprising topically administering thereto a therapeutically effective amount of a composition consisting essentially of about 0.5 to about 2.0 percent by weight/volume of a pharmaceutically acceptable, water soluble zinc salt and about 0.5 to about 2.0 percent by weight/volume of ascorbic acid or sodium ascorbate.

6. The method according to claim 5 wherein the composition has a pH from about 4 to about 5 and includes ZnSO.sub.4.7H.sub.2 O and sodium ascorbate.

7. The method according to claim 6 wherein the ratio of the ZnSO.sub.4.7H.sub.2 O to the sodium ascorbate is substantially 1 to 1 by weight.

8. A method for treating pregnancy gingivitis comprising topically administering to oral tissues a therapeutically effective amount of a composition consisting essentially of about 0.5 to about 2.0 percent by weight/volume of a pharmaceutically acceptable, water soluble zinc salt and about 0.5 to about 2.0 percent by weight/volume of ascorbic acid or sodium ascorbate.

9. A method for treating oral canker sores comprising topically administering to oral tissues a therapeutically effective amount of a composition consisting essentially of about 0.5 to about 2.0 percent by weight/volume of a pharmaceutically acceptable, water soluble zinc salt and about 0.5 to about 2.0 percent by weight/volume of ascorbic acid or sodium ascorbate.

10. A method for treating idopathic hypogeusia comprising topically administering to oral tissues a therapeutically effective amount of a composition consisting essentially of about 0.5 to about 2.0 percent by weight/volume of a pharmaceutically acceptable, water soluble zinc salt and about 0.5 to about 2.0 percent by weight/volume of ascorbic acid or sodium ascorbate.
Other info:

Inventors: Fahim, Mostafa S. (Columbia, MO, US)
Miller, Ercell L. (Columbia, MO, US)

Application Number: 935247
Filing Date: 1978-08-21
Publication_date: 1980-10-21
Assignee:
Primary Class(es): 424/49 424/642, 514/474
Other Classes:
US Patent Ref:

1488097	Mar, 1924	Greger	424/145.
2470906	May, 1949	Taylor	424/55.
3065139	Nov, 1962	Ericsson et al.	424/130.
3772431	Nov, 1973	Mlkvy et al.	424/49.
3886265	May, 1975	Evers et al.	424/49.
3888976	Jun, 1975	Mlkvy et al.	424/49.
4022880	May, 1977	Vinson et al.	424/49.

Other Refs: 7102423

Aug, 1972	NL

Primary Examiner: Robinson, Douglas W.
Assistant Examiner:
Attorney: Fishel; Grace J.