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Primary Examiner: Drezin, Norman A.
Assistant Examiner:
Attorney: Pearlman; Robert I.

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Title: Orally administered drug composition for therapy in the treatment of narcotic drug addiction

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Claims: We claim:

1. A solid composition for the oral treatment of narcotic addiction which is dispersible for dissolution before ingestion, said composition comprising:

a. an effective amount of methadone or its acid salts, and

b. an ingestible solid in a weight ratio of 10:1 to 40:1 per part of methadone in an amount sufficient to cause a rapid increase in viscosity during evaporation of an aqueous solution of the composition, wherein said ingestible solid is lactose, sucrose, mannitol, sorbitol, starch, microcrytalline cellulose, sodium carboxymethyl cellulose, methylcellulose ethylcellulose, carrageenin, gum tragacanth, gum acacia or polyvinylpyrrolidone.

2. The composition of claim 1 which further contains NHCO.sub.3 as a precipitating agent.
Other info:

Inventors: Shaw, Irving F. (East Rockaway, NY, US)
Berk, Jerome (New Rochelle, NY, US)

Application Number: 544360
Filing Date: 1975-01-27
Publication_date: 1976-09-14
Assignee: West Laboratories, Inc. (Long Island City, NY)
Primary Class(es): 514/648 514/23, 514/54, 514/57, 514/60, 514/738, 514/812
Other Classes:
US Patent Ref:

3173835	Mar, 1965	Weiner et al.	424/361.
3551133	Dec, 1970	Sprayberry et al.	424/361.
3555151	Dec, 1966	Kaplan et al.	424/361.

Other Refs: 1,601,446

Oct, 1970	FR

Other References: Remington's Practice of Pharmacy, (1961), pp. 446-448.
Carnie, Chemical Abstracts, 62; 8933a, (1965).
Laszlo, Chemical Abstracts, 56:8854-8855, (1962).
Nishide, Chemical Abstracts, 57:10546a, (1962).