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Title: Moisturizing units and moisturizing compositions containing the same



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Claims: What is claimed is:

1. A liposome comprising

i. a matrix of a ternary lipid mixture comprising about 50 to about 80 molar proportions of lecithin; about 10 to about 30 molar proportions of dicetyl phosphate; and about 10 to about 30 molar proportions of a sterol or caprolactum, said sterol being selected from the group consisting of cholesterol, phytosterol, sitosterol, sitosterol pyroglutamate, 7-dehydrocholesterol, lanosterol and mixtures thereof; and

ii. an aqueous solution of a humectant disposed interiorly of said liposome, said humectant being selected from the group consisting of glycerol, urea, sodium pyroglutamate, ornithine, and the Spier-Pascher water solubles;

said liposome having a substantially continuous outer surface.

2. A method for moisturizing keratinous matter of a living mammal comprising applying to said keratinous matter an effective amount of the liposome claimed in claim 1.

3. The liposome in accordance with claim 1 wherein said sterol is cholesterol.

4. The liposome in accordance with claim 1 wherein said sterol is phytosterol.

5. The liposome in accordance with claim 1 wherein said sterol is sitosterol.

6. The liposome in accordance with claim 1 wherein said sterol is sitosterol pyroglutamate.

7. The liposome in accordance with claim 1 wherein said sterol is 7-dehydrocholesterol.

8. The liposome in accordance with claim 1 wherein said sterol is lanosterol.

9. The liposome in accordance with claim 1 wherein said humectant is glycerol.

10. The liposome in accordance with claim 1 wherein said humectant is urea.

11. The liposome in accordance with claim 1 wherein said humectant is sodium pyroglutamate.

12. The liposome in accordance with claim 1 wherein said humectant is ornithine.

13. The liposome in accordance with claim 1 wherein said humectant is the Spier-Pascher water-solubles.

14. A composition capable of moisturizing keratinous matter of a living mammal, comprising an effective amount of the liposome described in claim 1 in a physiologically acceptable vehicle.

15. The composition in accordance with claim 14 wherein said vehicle is a skin cream.

16. The composition in accordance with claim 14 wherein said vehicle is a shampoo.

17. The composition in accordance with claim 14 wherein said vehicle is a brilliantine.
Other info:


Inventors: Oleniacz, Walter S. (Ringwood, NJ, US)

Application Number: 492369
Filing Date: 1974-07-29
Publication_date: 1976-05-18
Assignee: Lever Brothers Company (New York, NY)
Primary Class(es): 424/450 424/70.21, 424/70.22, 510/121, 510/122, 510/125, 510/158, 510/438, 510/468, 514/76
Other Classes:
US Patent Ref:
2756178Jul, 1956Verblen424/70.
3235457Feb, 1966Laden424/70.
3335053Aug, 1967Weitzel424/365.
3471624Oct, 1969Youngblood424/365.
3533955Oct, 1970Pader et al.424/70.
3535427Oct, 1970Millar et al.424/365.
3590123Jun, 1971Melloh et al.424/70.
3660566May, 1972Vinson et al.424/365.
3697644Oct, 1972Laiderman424/70.
3835169Sep, 1974Kraft et al.424/70.

Other Refs:
Primary Examiner: Rosen, Sam
Assistant Examiner: Clarke, Vera C.
Attorney: Dusyn; Kenneth F., Farrell; James J., Grant; Arnold