Title: Medicine containing the main sapogenin of helleborus

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Claims: What is claimed is:

1. A pharmaceutical composition useful in the treatment of ulcers comprising an effective amount of the main sapogenin of the roots and rhizomes of Helleborus species and a non-toxic pharmaceutically acceptable carrier, said sapogenin having the formula ##SPC2##

2. A pharmaceutical composition according to claim 1 in the form of a tablet, dragee or capsule.

3. A pharmaceutical composition according to claim 2 in the form of a tablet.

4. A pharmaceutical composition according to claim 2 in the form of a gelatin capsule.

5. A process of treating an ulcer to heal the ulcer in a mammal comprising administering to the mammal an effective amount of the sapogenin composition of claim 1 to heal the ulcer.

6. The process of claim 5 wherein the composition is administered orally, parenterally, rectally, vaginally, perlinqually or locally.

7. The process of claim 6 wherein the composition is administered orally.

8. The process according to claim 7 wherein the composition is administered in a dosage 50 to 500 mg of the sapogenin per kilogram of body weight.

9. The process of claim 5 wherein the ulcer treated is in the stomach or small intestine.

Other info:

Inventors: Isaac, Otto (Bruchkobel, DT)

Application Number: 565697
Filing Date: 1975-04-07
Publication_date: 1976-05-11
Assignee: Deutsche Gold- und Silber-Scheideanstalt vormals Roessler (DT)
Primary Class(es): 514/172 435/209, 435/267, 435/915, 435/916, 435/917, 435/918, 540/20
Other Classes:
US Patent Ref:
Other Refs: 23,66M

Mar, 1964	FR

Primary Examiner: Love, Ethel G.
Assistant Examiner:
Attorney: Cushman, Darby & Cushman