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Title: Method for the growth restriction of undesirable digestive system bacteria in animals and the establishment of lactobacillus lactis NRRL B-5628



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Claims: I claim:

1. The method for changing the digestive system bacteria in animals which comprises:

orally feeding a live bacterial composition of Lactobacillus lactis NRRL B-5628 mixed with a growth medium to said animals in an amount of at least 1 .times. 10.sup.10 cells per day per kg body weight of the animal and for a length of time sufficient to substantially reduce the number of such other digestive system bacteria and to achieve population dominance of NRRL B-5628 in the digestive system.

2. The method of claim 1 wherein the NRRL B-5628 is in the form of an unconcentrated fermentate in the growth medium.

3. The method of claim 1 wherein the amount is fed in range of 1 .times. 10.sup.10 to 1 .times. 10.sup.11 cells per day per kg body weight of the animal in a feed material.

4. The method of claim 1 wherein the animal is a piglet with E. coli in the intestine which can produce scours and wherein the amount of NRRL B-5628 fed in range of 1 .times. 10.sup.10 to 1 .times. 10.sup.11 cells per day per kg body weight.

5. The method of claim 1 wherein the animal is about to bear young.

6. The method of claim 1 wherein the animal is a chicken and the NRRL B-5628 is in the crop.

7. The method of claim 1 wherein the composition is initially in frozen form with a stabilizing agent and is thawed for use with cooling to maintain the viability.

8. The method of claim 7 wherein the bacterial composition is frozen to below about minus 28.9.degree.C and then thawed for oral feeding to a temperature less than about 10.degree.C.

Other info:


Inventors: Farr, Stewart M. (Sarasota, FL, US)

Application Number: 440250
Filing Date: 1974-02-06
Publication_date: 1976-04-27
Assignee: Microlife Technics, Inc. (Sarasota, FL)
Primary Class(es): 426/2 424/93.45, 426/71, 426/807
Other Classes:
US Patent Ref:
3326693Jun, 1967Reuter426/43.
3561977Feb, 1971Rothchild et al.99/109.
3677897Jul, 1972Jeffreys195/96.

Other Refs: 2,427M46-15643
Mar, 1964FR
Apr, 1971JA

Primary Examiner: Yudkoff, Norman
Assistant Examiner: Ribando, Curtis P.
Attorney: Miller, Morriss, Pappas & McLeod