Title: 6-Substituted-hydrocarbon-2-(substituted-thio)penem-3-carboxylic acids

Abstract: 6-Substituted-hydrocarbon-2-(substituted-thio)penem-3-carboxylic acids and congeners having useful antibacterial activity are disclosed. The compounds are prepared in a reaction sequence starting with a 4-acyloxy-2-azetidinone.

Do you think this is a good invention? Vote now:

Votes so far: For:(0) Against:(0)
Other info:

Inventors: Mccombie, Stuart W. (West Orange, NJ)

Application Number: 06/324317
Filing Date: 1981-11-23
Publication_date: 1983-12-27
Assignee: SCHERING CORP (US)

Primary Class(es): 514/195 987/368, 514/196, 514/197, 540/310
Other Classes: C07D205/08; C07D205/09; C07D499/88; C07F7/10; C07F9/568; C07D205/00; C07D499/00; C07F7/00; C07F9/00; A61K31/425; C07D499/00
US Patent Ref:

4168314	September, 1979	Christensen et al.	260/245.2R	6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
4282150	August, 1981	Menard	260/245.2R	2,6-Disubstituted penem compounds
4283531	August, 1981	Ganguly et al.	260/245.2R	Synthesis of ?-lactams having a substituted hydroxymethylene group at the position ? to the lactam c

Other Refs:
Primary Examiner: Rizzo, Nicholas S.
Assistant Examiner:
Attorney: Rosen, Gerald S.
Eisen, Bruce M.
King, Mary S.

Parent Case Data:

This application is a continuation-