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Title: 9-(1,3-Dihydroxy-2-propoxymethyl)guanine as antiviral agent

Abstract: The compound 9-(1,3-dihydroxy-2-propoxymethyl)guanine and the pharmaceutically acceptable salts thereof are useful as antiviral agents.


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Inventors: Verheyden, Julien P. H. (Los Altos, CA)
Martin, John C. (Redwood City, CA)

Application Number: 06/380969
Filing Date: 1982-05-24
Publication_date: 1983-12-27
Assignee: SYNTEX INC (US)

Primary Class(es): 514/263.380 544/277, 514/934, 544/276
Other Classes: C07D473/00; A61K31/52
US Patent Ref:
4146715March, 1979Schaeffer544/2762-Amido-9-(2-acyloxyethoxymethyl)hypoxanthines
4199574April, 1980Schaeffer544/276Methods and compositions for treating viral infections and guanine acyclic nucleosides
4323573April, 1982Schaeffer544/277Adenine derivatives
4340726July, 1982Simon et al.544/253Esters
4347360August, 1982Ogilvie544/276Ring open nucleoside analogues
4355032October, 1982Verheyden et al.424/2539-(1,3-Dihydroxy-2-propoxymethyl)guanine as antiviral agent

Other Refs:
Primary Examiner: Rizzo, Nicholas S.
Assistant Examiner:
Attorney: Moore, Annette M.
Moran, Tom M.
Parent Case Data:

This is a continuation-in-part of Ser. No. 267,210 filed May 21, 1981