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Title: 3-Substituted-2-propenimidamides and method of manufacturing the same

Abstract: New derivatives of 3-furyl-, 3-thienyl- and 3-phenyl-2-propenimidamides are disclosed, which are useful as anti-ulcer agents. These new compounds are synthesized by reacting an imino ether derived from a corresponding 3-substituted-2-propenenitrile with a suitable amine.


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Inventors: Tomiyama, Tsuyoshi (Sakaki, JP)
Tomiyama, Akira (Togura, JP)

Application Number: 06/289903
Filing Date: 1981-08-04
Publication_date: 1983-10-04
Assignee: KOTOBUKI SEIYAKU CO LTD (JP)

Primary Class(es): 514/438 564/47, 514/609, 558/9, 564/105, 514/618, 514/597, 55
Other Classes: C07C275/44; C07D307/54; C07D333/24; C07C275/00; C07D307/00; C07D333/00; A61K31/165; A61K31/275; A61K31/34; A61K31/38
US Patent Ref:
4252819February, 1981Hirata et al.549/76Antisecretory heterocyclic amidine compounds

Other Refs:
Primary Examiner: Siegel A.
Assistant Examiner:
Attorney: Burns, Robert E.
Lobato, Emmanuel J.
Adams, Bruce L.
Claims: