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Title:
β-Lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them
Abstract:
The present invention provides the compounds of the formula (II): ##STR1## and pharmaceutically acceptable salts and cleavable esters thereof wherein RCONH is an organic acylamino group and E is a carboxy group or pharmaceutically acceptable salt or ester thereof or is a cyano group. Their preparation is described as is their use in compositions containing them. Compounds wherein RCONH is replaced by an azido group are described as useful intermediates.
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Inventors:
Pearson, Michael J. (Horsham, GB2)
Branch, Clive L. (Horsham, GB2)
Application Number:
06/233180
Filing Date: 1981-02-10 Publication_date: 1983-10-04 Assignee:
BEECHAM GROUP LTD (GB)
Primary Class(es):
514/210.090
424/114, 987/368, 514/191, 514/339, 546/276.7 Other Classes:
C07D205/085; C07D477/24; C07F7/18; C07F9/568; C07D205/00; C07D477/00; C07F7/00; C07F9/00; C07D487/04; A61K31/40
Primary Examiner:
Lee, Mary C.
Assistant Examiner:
Attorney:
Jacobs & Jacobs
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