Title: N-phenoxy(or thio)hydrocarbon 3,4,5-trihydroxypiperidine derivatives, their use in medicine and in animal nutrition

Abstract: The invention relates to 3,4,5-trihydroxypiperidine compound of Formula (I) as methods for the preparation of said compounds. Also included in the invention are compositions containing said piperidine compounds and methods for the use of said piperidine compounds and compositions. The invention further includes veterinary compositions containing said piperidine compounds and their use in animal nutrition.

The piperidine compounds of Formula (I) are useful as agents against prediabetes, gastritis, constipation, infections of the gastro-intestinal tract, meteorism, flatulence, caries, arteriosclerosis and hypertension and in particular against diabetes, hyperlipaemia and adiposity, and also in animal nutrition for influencing the meat/fat ratio in favor of the meat content.

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Inventors: Junge, Bodo (Wuppertal, DE)
Stoltefuss, Jurgen (Haan, DE)
Muller, Lutz (Wuppertal, DE)
Krause, Hans-peter (Wuppertal, DE)
Sitt, Rudiger (Wuppertal, DE)

Application Number: 06/231695
Filing Date: 1981-02-05
Publication_date: 1983-10-04
Assignee: BAYER AG (DE)

Primary Class(es): 514/319 514/328, 546/220, 546/219, 546/208
Other Classes: A23K1/16; C07D211/46; C07D211/00; A61K31/445; C07D211/40
US Patent Ref:

4182767	January, 1980	Murai et al.	424/267	Antihyperglycemic N-alkyl-3,4,5-trihydroxy-2-piperidine methanol
4260622	April, 1981	Junge et al.	546/219	Animal feedstuffs employing 3,4,5-trihydroxypiperidines
4278683	July, 1981	Stoltefuss	546/219	Saccharase inhibiting 3,4,5-trihydroxypiperidine derivatives

Other Refs:
Primary Examiner: Fan, Jane T.
Assistant Examiner:
Attorney: Sprung, Horn, Kramer & Woods

Claims: