Title: Process for the preparation of L-proline by cultivating algae

Abstract: A process for producing L-proline by cultivating Chlorella sp. 580 algae under high-intensity illumination in an aqueous growth medium containing a high concentration of sodium chloride (at least 1 M in the final stage of cultivation), providing an adequate supply of carbon, in a depth not exceeding approximately 20 cm of the aqueous medium, until algae of high L-proline content are obtained, harvesting the algae and thereafter recovering L-proline from the algae.

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Inventors: Leavitt, Richard I. (Baton Rouge, LA)

Application Number: 06/329226
Filing Date: 1981-12-10
Publication_date: 1983-05-10
Assignee: ETHYL CORP

Primary Class(es): 435/107 435/946
Other Classes: C12N1/12; C12P13/24; C12P13/00; C12R1/89; C12P13/24
US Patent Ref:

4224409

September, 1980

Nakamori et al.

435/107

Method for producing L-proline by fermentation

Other Refs: GB1132036

October, 1968

Other References: Aust. J. Plant Physiology, 1979, vol. 6, pp. 69-79.
Limnol. Oceanographer, vol. 10, pp. 192-206 (1965).

Primary Examiner: Shapiro, Lionel M.
Assistant Examiner:
Attorney: Johnson, Donald L.
Sieberth, John F.
Montgomery, Willard G.

Clai