Title: Process for the production of human chorionic gonadotropin

Abstract: The present invention relates to a process for the production of human chorionic gonadotropin (hCG).

More precisely, the invention relates to a process for the mass production of hCG, comprising in vivo multiplication of human lymphoblastoid cells capable of producing hCG, and hCG production by the multiplied human lymphoblastoid cells.

The hCG production according to the invention is extremely higher, in terms of hCG production per cell, than that attained by conventional process using in vitro tissue culture; thus, hCG can be used in a sufficient amount in the prevention and treatment of human diseases.

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Inventors: Sugimoto, Kaname (Okayama, JP)

Application Number: 06/290863
Filing Date: 1981-08-07
Publication_date: 1983-05-10
Assignee: Hayashibara, Biochem Lab (JP)

Primary Class(es): 435/70.200 435/70.400, 530/398
Other Classes: C07K14/59; A61K38/00; C07K14/435; C12P21/02; C12P21/00; C12P21/04
US Patent Ref:

4288546

September, 1981

Narasimhan et al.

435/70

Process for the large scale production of pituitary hormones by serial secondary suspension culture

Other Refs:
Primary Examiner: Rosen, Sam
Assistant Examiner:
Attorney: Browdy, And Neimark

Claims:

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