Title: Process for the production of human follicle-stimulating hormone

Abstract: The present invention relates to a process for the production of human follicle-stimulating hormone (hFSH).

More precisely, the invention relates to a process for the mass production of hFSH, comprising in vivo multiplication of human cells capable of producing hFSH, and exposure of the multiplied human cells to a follicle-stimulating hormone inducer.

The hFSH production according to the invention is much higher than that attained by conventional processes using in vitro tissue culture; thus, hFSH can be used in a sufficient amount in the prevention and treatment of human diseases.

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Inventors: Sugimoto, Kaname (Okayama, JP)

Application Number: 06/290861
Filing Date: 1981-08-07
Publication_date: 1983-05-10
Assignee: Hayashibara, Biochem Lab (JP)

Primary Class(es): 435/70.200 435/70.300, 530/399
Other Classes: C07K14/59; A61K38/00; C07K14/435; C12P21/02; C12P21/00; C12P21/04
US Patent Ref:

4276282	June, 1981	Sugimoto et al.	435/68	Interferon and preparations containing interferon
4285929	August, 1981	Sugimoto et al.	435/68	Type II interferon and agents thereof
4288546	September, 1981	Narasimhan et al.	435/70	Process for the large scale production of pituitary hormones by serial secondary suspension culture
4328207	May, 1982	Sugimoto	435/68	Process for preparing mouse interferon

Other Refs: Other References: Chemical Abstracts, 91:86930s (1979).

Primary Examiner: Rosen, Sam
Assistant Examiner:
Attorney: Browdy, And Neimark

Claims:

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