Title: Postoperative treatment of carcinoma patients

Abstract: Cancer patients following surgery are treated to lessen pain, induce a feeling of well-being and increase appetite by administering to the mammal an effective dosage of a non-toxic dithiobis-heterocyclic compound, belonging to the class of thione-forming disulfides, such as 6,6'-dithiodinicotinic acid (CPDS) which is capable of preferentially reacting with peripheral rather than intracellular sulfhydryl groups. In addition to this blocking effect, treatment with compounds of this type also has the effect of modifying the electric charge of cell surfaces. This blocking of peripheral sulfhydryl groups is not accompanied by toxic effects in laboratory mammals or in man.

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Inventors: Grassetti, Davide R. (26 Northgate Ave., Berkeley, CA, 94708)

Application Number: 06/219812
Filing Date: 1980-12-22
Publication_date: 1983-03-29
Assignee: Grassetti, Davide R.

Primary Class(es): 514/335 424/251, 424/270
Other Classes: A61K31/00; A61K31/425; A61K31/455; A61K31/505
US Patent Ref:

3698866

October, 1972

Grassetti

232/30R

Other Refs: Other References: Chemical Abstracts 70: 95124a, (1969).

Primary Examiner: Goldberg, Jerome D.
Assistant Examiner:
Attorney: Nields, Henry C.

Parent Case Data: CROSS REFERENCES TO RELATED APPLICATIONS

The present application is a continuation in part of my