Title: 6-{3-[4-(Substituted benzyl)-1-piperazinyl]propyloxy}-4,9-dihydro-4,9-dioxo-1H-naphtho[2,3-d-]- v

Abstract: Compounds of formula (I): ##STR1## wherein R is hydrogen, halogen, C₁-4 alkyl or C₁-4 alkoxy; R₁ is hydrogen or C₁-6 alkyl; and n is 1 to 6 and pharmaceutically acceptable salts thereof; pharmaceutical compositions containing them; a process for their preparation; and their use in treating allergy.

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Inventors: Buckle, Derek R. (Redhill, GB2)
Smith, Harry (Maplehurst, Near Horsham, GB2)
Tedder, John M. (Redhill, GB2)

Application Number: 06/254372
Filing Date: 1981-04-15
Publication_date: 1983-03-29
Assignee: BEECHAM GROUP LTD (GB)

Primary Class(es): 514/254.060 548/259, 514/826, 544/366
Other Classes: C07D249/22; C07D249/00
US Patent Ref:

4263299	April, 1981	Buckle et al.	544/250
4263309	April, 1981	Buckle et al.	544/250

Other Refs: Other References: McOmie, J. F., "Protective Groups in Organic Chemistry", pp. 197-199, (1973).

Primary Examiner: Daus, Donald G.
Assistant Examiner: Gibson, Sharon A.
Attorney: Jacobs & Jacobs

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