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Title: Penetrating topical medicament
Abstract:
An improved topical medicament useful in treating athletic injuries or other painful subdermal conditions is provided which includes a penetrating solvent such as dimethylsulfoxide (DMSO) along with, in preferred forms, a corticosteroid (e.g., hydrocortisone acetate), a counterirritant/analgesic such as methyl salicylate, and one or more emulsifiers, a rubifacient and an alcoholic carrier. The medicaments hereof, when applied topically, are absorbed through the skin and serve to transport the corticosteroid and/or analgesic to a site of inflammation. The preferred salicylate component is converted to the analgesic salicyic acid and active metabolites in the bloodstream to serve as a pain killing agent (i.e., a prostaglandin inhibitor). The compositions hereof may be in the form of lotions, creams or aerosols, depending upon desired end use.
Other info: Inventors: Levy, Michael A. (9911 Campbell, Kansas City, MO, 64131) Application Number: 06/271427 Filing Date: 1981-06-08 Publication_date: 1982-10-12 Assignee: Levy, Michael A. Primary Class(es): 514/162 514/946, 514/164, 424/742, 514/936, 514/171 Other Classes: A61K31/57; A61K31/60; A61K47/20 US Patent Ref:
Other Refs: Other References: Merck Index, 9th Ed., (1976), p. 433. Primary Examiner: Friedman, Stanley J. Assistant Examiner: Attorney: Schmidt, Johnson, Hovey & Williams Claims:
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