Title: Antibiotic composition of matter

Abstract: Novel antibiotic U-61,732 producible in a fermentation under controlled conditions using a biologically pure culture of the microorganism Saccharopolyspora hirsuta strain 367, NRRL 12045. This antibiotic is active against gram-positive bacteria, for example, Staphylococcus aureus. Also disclosed are the 11-acyl esters of U-61,732. Thus, these compounds can be used in various environments to eradicate or control such bacteria.

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Inventors: Whaley, Howard A. (Portage, MI)
Coats, John H. (Kalamazoo, MI)

Application Number: 06/180529
Filing Date: 1980-08-25
Publication_date: 1982-09-28
Assignee: UPJOHN CO

Primary Class(es): 548/526 548/256, 435/119, 548/311.700, 548/364.400, 548/214,
Other Classes: C07D493/10; C12P17/18; C07D493/00; C07D493/08
US Patent Ref:

4148883

April, 1979

Celmer et al.

424/122

Antibiotics produced by new species of nocardia

Other Refs: Other References: Celmer et al.; J.A.C.S., vol. 102, pp. 1403-1409, (6/4/80).

Primary Examiner: Lee, Mary C.
Assistant Examiner:
Attorney: Saliwanchik, Roman

Claims:

We claim