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Title: 1-(Trialkylamino)-3-(phenylphenoxy)-2-propanol quarternary salts

Abstract: The above captioned compounds exhibit potent and long acting anti-arrhythmic activity while lacking the undesirable side effects, e.g. .beta.-adrenergic receptor blocking activity and local anesthetic activity, characteristic of related prior art compounds.


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Inventors: Counsell, Raymond E. (Ann Arbor, MI, US)
Lucchesi, Benedict R. (Ann Arbor, MI, US)

Application Number: 780880
Filing Date: 1977-03-24
Publication_date: 1980-12-23
Assignee: The Regents of the University of Michigan (Ann Arbor, MI)
Primary Class(es): 514/643 514/821, 564/287
Other Classes:
US Patent Ref:
3328464Jun, 1967Gundel260/567.
3840666Oct, 1974Lucchesi424/329.

Other Refs: 1197755
Jul, 1970GB

Primary Examiner: Waddell, Frederick E.
Assistant Examiner:
Attorney: Olsen and Stephenson