Title: Carbamates of homolysergols (8.beta.-hydrohyethylergolines) and compositions thereof

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Abstract: Novel ergoline derivatives are disclosed having the general formula (I) ##STR1## wherein R.sub.1 is hydrogen, and alkyl radical (C.sub.1 to C.sub.4) either straight of branched chain, Z is hydrogen, bromine, S-R.sub.IV (in which R.sub.IV is an alkyl of from C.sub.1 to C.sub.4, R.sub.II is equal to R.sub.III and is an alkyl of from C.sub.1 to C.sub.6, or R.sub.II united with R.sub.III by-(CH.sub.2).sub.n, with n from 0 to 7, to form simple heterocyclic compounds such as pyrrolidine, piperidine, hexamethyleneimine, or united with --(CH.sub.2).sub.n --A--(CH.sub.2).sub.n, with n equal to a number from 2 to 5 to form heterocyclic compounds such as A=0 and n=2 to give morpholine, A is N-R.sub.V and N=2 for piperazine, either substituted or unsubstituted, with R.sub.V being hydrogen, an alkyl of from C.sub.1 to C.sub.4, or a phenyl radical, the x--y bridge being a ##STR2## bond. A method for the preparation of such compounds and pharmaceutical compositions thereof are also disclosed.


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