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Primary Examiner: Frinks, Ronald L.
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Title: Heart valve prosthesis and method for the production thereof

Abstract: A flexible non-stented heart valve prosthesis made from a flat piece of a stabilized biological membrane. The membrane is folded along one or more folding lines and attached to a flat flexible non-biological base material so that one or more leaflets are formed. Preferably the membrane is pericardium and is attached by machine stitching to a woven polymeric base material. Different valve types including ventricular outflow patches and three-leaflet valves such as aortic valves and methods for their production are described. The aortic valve is preferably made from three separate leaflets provided with narrow base materials serving as attachment margins which are stitched together in a manner to form a three-leaflet valve.


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Inventors: Rygg, Inge H. (Charlottenlund, DK)

Application Number: 907580
Filing Date: 1978-05-19
Publication_date: 1980-08-26
Assignee: Biocoating Anpartsselskab (Copenhagen, DK)
Primary Class(es): 623/2.15
Other Classes:
US Patent Ref:
3320972May, 1967High et al.3/1.
3548418Dec, 1970Angell et al.3/1.
3744062Jul, 1973Parsonnet3/1.
3755823Sep, 1973Hancock3/1.
3974526Aug, 1976Dardik et al.3/1.
3983581Oct, 1976Angell et al.3/1.
3988782Nov, 1976Dardik et al.3/1.

Other Refs: 492279
Jan, 1976SU
Other References: "Fascia Lata Replacement of Aortic Valves", by Ake Senning et al., The Journal of Thoracic and Cardiovascular Surgery, vol. 54, No. 4, Oct. 1967, pp. 465-470.
"The Autologous Rectus Sheath Cardiac Valve", by C. L. Athanasuleas et al., The Journal of Thoracic & Cardiovascular Surgery, vol. 65, No. 1, Jan. 1973, pp. 118-123.