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Primary Examiner: Schenkman, Leonard
Assistant Examiner:
Attorney: Newman; Irving

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Title: Zinc salt of all-trans-retinoic acid for the treatment of acne

Abstract: A zinc salt of retinoic acid has been prepared and found to have significant anti-acne activity, similar to that of retinoic acid, but with less of a tendency to cause flaking or irritation at anti-acne effective concentrations.


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Inventors: Papa, Christopher M. (Colts Neck, NJ, US)

Application Number: 955997
Filing Date: 1978-10-30
Publication_date: 1980-07-22
Assignee: Johnson & Johnson (New Brunswick, NJ)
Primary Class(es): 514/494 514/784, 514/787, 554/75, 556/131
Other Classes:
US Patent Ref:
3729568Apr, 1973Kligman424/318.
3856941Dec, 1974Turner424/145.
3906108Sep, 1975Felty424/318.
3949072Apr, 1976Tenta424/145.
4039681Aug, 1977Abdel-Monem424/289.
4053630Oct, 1977Yu et al.424/289.

Other Refs: 1476717
Jun, 1977GB.
Other References: Chemical Abstracts 76:158354x (1972).