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Title: Mercaptoacyldihydropyrazole carboxylic acid derivatives

Abstract: Hypertension can be treated using compounds having the formula or a basic salt thereof, wherein R.sub.1 is hydrogen, alkyl, aryl, arylalkyl or ##STR1## wherein R.sub.5 is alkyl or aryl; R.sub.2 is hydrogen or alkyl; R.sub.3 is aryl; R.sub.4 is hydrogen, alkyl or arylalkyl and n is 0, 1 or 2.


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Inventors: Rovnyak, George C. (Hopewell, NJ, US)

Application Number: 018548
Filing Date: 1979-03-08
Publication_date: 1980-07-08
Assignee: E. R. Squibb & Sons, Inc. (Princeton, NJ)
Primary Class(es): 514/403 548/379.4
Other Classes:
US Patent Ref:
4105776Aug, 1978Ondetti et al.424/274.
4129566Dec, 1978Ondetti et al.546/326.

Other Refs: 861454
Jun, 1978BE

Primary Examiner: Rotman, Alan L.
Assistant Examiner: Harkaway, Natalia
Attorney: Levinson; Lawrence S., Barrack; Donald J.