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Primary Examiner: Ford, John M.
Assistant Examiner: Schwartz, Richard A.
Attorney: Silverstein; M. Howard, McConnell; David G., Ribando; Curtis P.

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Title: Sesbanine and the use thereof in treating leukemic tumors

Abstract: A novel alkaloid compound named "sesbanine" has been produced from the tissue of a leguminous plant known as Sesbania drummondii. Sesbanine has proven to be effective in causing the remission of leukemic tumors in animals and is characterized by the following structural formula: ##STR1##

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Inventors: Powell, Richard G. (Peoria, IL, US)

Application Number: 025131
Filing Date: 1979-03-29
Publication_date: 1980-04-29
Assignee: The United States of America as represented by the Secretary of (Washington, DC)
Primary Class(es): 514/278 546/18
Other Classes:
US Patent Ref:

3406175	Oct, 1968	Lesher	546/18.
3649635	Mar, 1972	Von Strandtmann et al.	546/18.
3936459	Feb, 1976	Kato et al.	546/18.
3947451	Mar, 1976	Jonsson et al.	546/18.

Other Refs: Other References: Dorland's Illustrated Medical Dictionary, 25th Ed., _W. B. Saunders, Philadelphia, pp. 896-897 and 1024.
Durant, J., et al., The Chronic Leukemias, Chas. C. Thomas, _Springfield, Ill., 1972, pp. 54-57.
Geran, R., et al., Cancer Chemotherapy Reports, Part 3, _vol. 3, No. 2, Sep. 1972, pp. 1-9.
Kingsbury, J., Poisonous Plants Of The United States And Canada, Prentice Hall, Englewood Cliffs, N.J., 1964, pp. 353-357.
Robey, A., Isolation Of The Toxin In Daubentonia Longifolia, _Thesis, Texas A and M Coll. (1925).
Powell, R., et al., Planta Med. 1976, 30(1), 1-8.