Title: Indole derivatives and therapeutically acting drugs

Abstract: The invention relates to new indole derivatives, their preparation and use as drugs. Said compounds may be represented by the general formula ##STR1## in which R represents a hydrogen atom or an alkyl or benzyl group and Z represents a hydrogen atom or a halogen atom or an alkyl, hydroxy, acyloxy, carbamate or methoxy group. They are prepared by reacting tryptamine derivatives with synthons of the formula ##STR2## in which X and Y each represent an oxygen or sulphur atom, and R.sub.1 and R.sub.2 each represent an alkyl or phenyl radical or form together an alkylidene chain. They may be used as intermediate compounds for chemical syntheses and also as drug for treating cerebro-vascular and cardio-circulatory insufficiencies.

Do you think this is a good invention? Vote now:

Votes so far: For:(0) Against:(0)
Other info:

Inventors: Hannart, Jean A. A. J. (Chaumont-Gistoux, BE)

Application Number: 946456
Filing Date: 1978-09-27
Publication_date: 1980-04-29
Assignee: Omnium Chimique Societe Anonyme (Louvain-la-Neuve, BE)
Primary Class(es): 514/288 546/66
Other Classes:
US Patent Ref:
Other Refs: Other References: Pinar et al., Chemical Abstracts, vol. 80 (1974) 60060f.