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Primary Examiner: Rosen, Sam
Assistant Examiner:
Attorney: Ross; Karl F.

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Title: Treating mammalian subject sensitive to indomethacin ulcerogenisis

Abstract: Ulcer production in animals is prevented during prolonged antiphlogistic treatment with ulcerogenic quantities of indomethacin by using it in a composition of 1 part of indomethacin to 7.5 to 25 parts, preferably 10 parts by weight of a salicylate. Indomethacin is the most potent ulcerating compound among approved non-steroid antiinflammatory agents.

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Inventors: Ezer, Elemer (Budapest, HU)
Szporny, Laszlo (Budapest, HU)
Forgach, Lilla (Budapest, HU)
Palosi, Eva (Budapest, HU)
Cholnoky, Eszter (Budapest, HU)
Karpati, Egon (Budapest, HU)
Hajos, Gyorgy (Budapest, HU)
Hortobagyi, Gyozo (Budapest, HU)
Gidai, Katalin (Budapest, HU)

Application Number: 931910
Filing Date: 1978-08-08
Publication_date: 1980-04-29
Assignee: Richter Gedeon Vegyeszeti Gyar Rt. (Budapest, HU)
Primary Class(es): 514/161 514/420
Other Classes:
US Patent Ref:
Other Refs: Other References: Hultmark et al.-Chem. Abst. vol. 83 (1975), p. 141,706k.
Gietka et al.-Chem. Abst. vol. 82 (1975), p. 291p.