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Title:
Cortisol radioimmunoassay method and cortisol derivatives useful therefor
Abstract:
The cortisol compound of the formula (E) ##STR1## wherein R represents a hydroxy group, a tyrosine lower alkyl ester residue, a tyramine residue, a histamine residue, a 7-aminoheptanoyl-tyrosine lower alkyl ester residue, a radioiodinated tyrosine lower alkyl ester residue, a radioiodinated tyramine residue, a radioiodinated histamine residue, a radioiodinated 7-aminoheptanoyltyrosine lower alkyl ester residue, a protein or a polypeptide; and a radioimmunoassay method using cortisol derivative.
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Inventors:
Kojima, Masaharu (Fukuoka, JP) Sone, Hisao (Fukuoka, JP) Ogawa, Hiroshi (Kashiwa, JP) Nakazawa, Nobuhiko (Urawa, JP) Tachibana, Seiji (Tokyo, JP)
Application Number:
802397
Filing Date: 1977-06-01 Publication_date: 1980-02-26 Assignee:
Daiichi Radioisotope Laboratories, Ltd. (Tokyo, JP)
Primary Class(es):
552/523
Other Classes:
US Patent Ref:
Other Refs:
Other References:
Weinstein et al., "Steroids", vol. 20, 1972, pp. 789-809. Feeser et al., "Steroids" Text, pp. 607 and 650. |