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Title: Oil-free adjuvant compositions containing N-acetyl-muramyl-L-alanyl-D-glutamic acid and method of use

Abstract: The invention pertains to drug oil-free compositions, notably aqueous injectable compositions acting as non-specific adjuvants to stimulate in a host the immune responses to different antigens. The active principle of these oil-free compositions is N-acetyl-muramyl-L-alanyl-D-glutamic acid.


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Inventors: Audibert, Francoise (Neuilly, FR)
Chedid, Louis (Paris, FR)
Lefrancier, Pierre (Bures sur Yvette, FR)
Choay, Jean (Paris, FR)
Lederer, Edgar (Sceaux, FR)

Application Number: 625195
Filing Date: 1975-10-23
Publication_date: 1979-10-23
Assignee: Agence Nationale de Valorisation de la Recherche (ANVAR) (Neuilly sur Seine, FR)
Primary Class(es): 424/279.1 424/45, 514/62
Other Classes:
US Patent Ref:
Other Refs: 2160326
Jun, 1973FR.
Other References: Adam et al., Chem. Abst., vol. 79 (1973), p. 30388f.