Title: Method of producing tumor antibodies

Abstract: Antibodies demonstrating a specificity for malignant tumors are produced by somatic cell hybrids between hypoxanthine phosphoribosyltransferase deficient myeloma cells and spleen or lymph cells derived from an animal previously primed with tumor cells.

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Inventors: Koprowski, Hilary (Wynnewood, PA, US)
Croce, Carlo M. (Philadelphia, PA, US)

Application Number: 901102
Filing Date: 1978-04-28
Publication_date: 1979-10-23
Assignee: The Wistar Institute (Philadelphia, PA)
Primary Class(es): 435/70.21 424/155.1, 436/548, 530/388.8
Other Classes:
US Patent Ref:
Other Refs: Other References: welsh-Nature, vol. 266, Apr. 1977, p. 495.
Galfre et al.-Nature, vol. 266, Apr. 1977, pp. 550-552.
Kohler et al.-Nature, vol. 256, Aug. 7, 1975, pp. 495-497.