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Title: Phthalidyl 2-(3'-trifluoromethyl-anilino)-pyridine-3-carboxylate and its salts

Abstract: A new phthalidylic eater of 2-(3'trifluoromethyl-anilino)-pyridine-3-carboxylic acid is prepared by reacting 2-(3'-trifluoromethylanilino)-pyridine-3-carboxylic acid with 3-bromophthalide and an organic base in a reaction medium comprising a solvent selected from the group consisting of acetone, dimethylformamide, dimethylacetamide and acetonitrile. The product has an antiinflammatory activity without the ulcerogenic effect that is characteristic of the corresponding acid.


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Inventors: Bago, Sebastian (Buenos Aires, AR, US)

Application Number: 879749
Filing Date: 1978-02-21
Publication_date: 1979-09-18
Assignee:
Primary Class(es): 514/337 546/284.1
Other Classes:
US Patent Ref:
3478040Nov, 1969Sherlock260/295.
3959272May, 1976Hoffman260/295.

Other Refs:
Primary Examiner: Rotman, Alan L.
Assistant Examiner:
Attorney: Kane, Dalsimer, Kane, Sullivan and Kurucz