Title: Process for producing fortimicin factors

Abstract: New antibiotic compounds, Fortimicin factors D and KE are produced by fermentation of microorganisms belonging to the genus Micromonospora. The antibiotic compounds are accumulated in the culture liquor and are isolated therefrom. A semisynthetic method of producing Fortimicin KE utilizing Fortimicin D is also disclosed.

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Inventors: Iida, Takao (Tokyo, JP)
Shirahata, Kunikatsu (Machida, JP)
Maisubara, Isao (Machida, JP)
Sugimoto, Masahiro (Shizuoka, JP)
Ishii, Shinzo (Shizuoka, JP)
Okachi, Ryo (Macheda, JP)
Nara, Takashi (Tokyo, JP)

Application Number: 845970
Filing Date: 1977-10-27
Publication_date: 1979-03-20
Assignee: Abbott Laboratories (Chicago, IL)
Primary Class(es): 435/125 435/863, 536/16.1, 549/419
Other Classes:
US Patent Ref:

3931400	Jan, 1976	Nara et al.	195/80.
3976748	Aug, 1976	Nara et al.	195/96.

Other Refs:
Primary Examiner: Tanenholtz, Alvin E.
Assistant Examiner:
Attorney: Fitzpatrick, Cella, Harper & Scinto