Title: Daunorubicin derivatives, their preparation and their use

Abstract: Daunorubicin (also known as daunomycin) derivatives of the formula ##STR1## wherein X is ##STR2## and R is --COCF.sub.3 or H which are prepared by hydrogenating 9-desacetyl-9-keto-N-trifluoroacetyldaunorubicin, an unexpectedly stable key-intermediate which is itself a new compound, are useful in treating certain mammalian tumors.

Do you think this is a good invention? Vote now:

Votes so far: For:(0) Against:(0)
Other info:

Inventors: Penco, Sergio (Milan, IT)
Angelucci, Francesco (Milan, IT)
Arcamone, Federico (Milan, IT)

Application Number: 810077
Filing Date: 1977-06-27
Publication_date: 1978-12-26
Assignee: Societa Farmaceutici Italia S.p.A. (Milan, IT)
Primary Class(es): 514/34 514/908, 536/6.4
Other Classes:
US Patent Ref:

4020270	Apr, 1977	Arcamone et al.	536/17.
4025623	May, 1977	Arcamone et al.	536/17.

Other Refs:
Primary Examiner: Brown, Johnnie R.
Assistant Examiner:
Attorney: Hubbell, Cohen, Stiefel & Gross