Title: Bis-quaternary pyridinium-2-aldoxime salts and a process for their preparation

Abstract: Bis-quaternary pyridinium-2-aldoxime salts of the formula ##STR1## wherein R is --CO--R.sup.1, --CO--NR.sup.2 R.sup.3 or --COOR.sup.4 ; R.sup.1 is alkyl of 1 - 6 carbon atoms, cyclohexyl, Ar or benzyl; R.sup.2 is H, alkyl of 1 - 6 carbon atoms, cyclohexyl, Ar, aralkyl of 7 - 13 carbon atoms or 2-pyrimidyl; R.sup.3 is alkyl of 2 - 6 carbon atoms, cyclohexyl, Ar, aralkyl of 7 - 13 carbon atoms or 2-pyrimidyl; R.sup.4 is alkyl of 2 - 6 carbon atoms, cyclohexyl, Ar or benzyl; Ar is phenyl or phenyl monosubstituted or polysubstituted by alkyl of 1 - 4 carbon atoms, methoxy, Cl, or naphthyl and X is Cl, Br or I, are antidotes for phosphorus-containing pesticides and chemical warfare agents.

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Inventors: Hagedorn, Ilse (Freiburg, DE, US)

Application Number: 786693
Filing Date: 1977-04-11
Publication_date: 1978-12-05
Assignee: Merck Patent Gesellschaft mit beschrankter Haftung (Darmstadt, DE)
Primary Class(es): 514/332 544/296, 544/331, 546/262, 546/263
Other Classes:
US Patent Ref:

3773775

Nov, 1973

Hagedorn

260/296.

Other Refs:
Primary Examiner: Rotman, Alan L.
Assistant Examiner:
Attorney: Millen & White