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Title: Preparation of cephalosporin compounds

Abstract: The invention relates to a novel method for the preparation of a 7.beta.-acylamido-3-bromomethylceph-3-em-4-carboxylic acid-1-oxide compound by brominating a 7.beta.-acylamido-3-methylceph-3-em-4-carboxylic acid-1-oxide compound.


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Inventors: Laundon, Brian (Northolt, GB)
Cowley, Brian Richard (Greenford, GB)
Humber, David Cedric (London, GB)

Application Number: 749300
Filing Date: 1976-12-10
Publication_date: 1978-09-12
Assignee: Glaxo Laboratories Limited (Greenford, GB)
Primary Class(es): 204/157.64 204/157.7
Other Classes:
US Patent Ref:
3544581Dec, 1970Essery204/158.
3652546Mar, 1972Cheney et al.204/158.

Other Refs:
Primary Examiner: Williams, Howard S.
Assistant Examiner:
Attorney: Bacon & Thomas