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Title:
Prostenoic acid derivatives
Abstract:
Prostenoic acid derivatives of the general formula ##STR1## wherein R.sup.1 is H or alkyl or 1-4 carbon atoms; R.sup.2 is alkyl of 5 - 9 carbon atoms, phenoxymethyl or phenoxymethyl substituted by up to 3 of F, Cl, Br, CH.sub.3, CF.sub.3, or OCH.sub.3 ; R.sup.3 is H or alkyl or 1 - 5 carbon atoms, and physiologically acceptable salts thereof, as well as intermediates therefore are blood-pressure lowering, vasodilatory, diuretic and nasal mucosa decongesting agents.
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Inventors:
Baumgarth, Manfred (Darmstadt, DT) Radunz, Hans-Eckart (Darmstadt, DT) Orth, Dieter (Darmstadt, DT) Lissner, Reinhard (Darmstadt, DT) Enenkel, Hans-Joachim (Darmstadt, DT) Zeelen, Filippus Johannes (Heesch, NL)
Application Number:
634349
Filing Date: 1975-11-24 Publication_date: 1978-04-25 Assignee:
Merck Patent Gesellschaft mit beschrankter Haftung (Darmstadt, DT)
Primary Class(es):
514/530
514/573, 560/61, 560/62, 560/121, 560/231, 560/255, 562/465, 562/503
Other Classes:
US Patent Ref:
Other Refs:
Other References:
chem. Abstracts 76, Index Guide, 131, (1972). |