Title: Neomycin and paromomycin derivatives

Abstract: The invention relates to novel neomycin and paromomycin derivatives having antibiotic activity. The derivatives have the formula: ##STR1## wherein R' is --NH.sub.2 or --OH, either R.sup.2 or R.sup.3 is --CH.sub.2 NH.sub.2 and the other is hydrogen, and in addition non-toxic pharmaceutically acid addition salts of these compounds can be used.

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Inventors: Hanessian, Stephen (Beaconsfield, CA, US)

Application Number: 690733
Filing Date: 1976-05-27
Publication_date: 1978-01-03
Assignee: Canadian Patents and Development Limited (Ottawa, CA)
Primary Class(es): 514/39 435/32, 435/194, 435/849, 435/875, 514/38, 536/13.2, 536/13.3
Other Classes:
US Patent Ref:

3860574	Jan, 1975	Naito et al.	536/12.
3897412	Jul, 1975	Naito et al.	536/17.
3923783	Dec, 1975	Naito et al.	536/17.
3956274	May, 1976	Umezawa et al.	536/17.

Other Refs:
Primary Examiner: Brown, Johnnie R.
Assistant Examiner:
Attorney: