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Primary Examiner: Phillips, Delbert R.
Assistant Examiner:
Attorney: Blanchard, Flynn, Thiel, Boutell & Tanis

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Title: Dopamine derivative compounds, preparation thereof and medicine containing same

Abstract: A novel dopamine derivative compound having the following general formula and pharmacologically acceptable acid addition salt thereof: ##STR1## wherein X stands for a di- or tri-peptide residue derived from alanine, glycine, glutamine, isoleucine, lysine, leucine, tyrosine proline or valine, having an excellent activity of increasing the renal blood flow are provided.

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Inventors: Yanaihara, Noboru (Shizuoka, JA)
Igarashi, Toshiji (Tokorozawa, JA)
Kunii, Youichi (Funabashi, JA)

Application Number: 715008
Filing Date: 1976-08-17
Publication_date: 1977-12-20
Assignee: Eisai Co., Ltd. (Tokyo, JA)
Primary Class(es): 514/19 260/1, 514/18, 530/331
Other Classes:
US Patent Ref:

3803120

Apr, 1974

Felix

424/177.

Other Refs: Other References: Jones et al.; Am. Chem. Soc., 165, Meet. Medi. 11, 1973.
John L. McNay et al.; Chem. Abst. 63, 1965, p. 8916g.
Sandler et al.; Prog. Med. Chem. 6, 200, 1969.
D. B. Calne et al.; Nature 226, 1970, pp. 21-24.