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Primary Examiner: Meyers, Albert T.
Assistant Examiner: Robinson, D. W.
Attorney: Burgess, Dinklage & Sprung

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Title: Rapidly resorbable glibenclamide

Abstract: A blood sugar lowering composition comprising as the active material particulate glibenclamide having a surface area of about 3 to 10 m.sup.2 /g in admixture with a pharmacologically acceptable non-ionic wetting agent present in about 2 to 20 times the weight of the glibenclamide. The preferred wetting agent is polyoxyethylene stearate present in about 5 to 10 times the weight of the glibenclamide.

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Inventors: Rothe, Werner (Hockenheim, DT)
Heinemann, Helmut (Heidelberg, DT)
Schmidt, Felix Helmut (Mannheim-Seckenheim, DT)
Betzien, Gunter (Mannheim, DT)

Application Number: 688435
Filing Date: 1976-05-20
Publication_date: 1977-11-29
Assignee: Boehringer Mannheim G.m.b.H. (Mannheim, DT)
Primary Class(es): 514/593 514/866
Other Classes:
US Patent Ref:

3507954

Apr, 1970

Weber et al.

424/321.

Other Refs: Other References: Remington's--Pharmaceutical Science--13th ed--J. Hoover Hack Publ. Co.--Easton, Pa., 1965, pp. 195-197, 332-333 & 420.