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Title: 7-(.alpha.-Substituted phenylacetamido)-3-(1-carboxymethylthioethyltetrazolyl-5-thiomethyl)-3-c ephem-4-carboxylic acids

Abstract: New semisynthetic cephalosporins characterized by having structures with a 1-carboxymethylthioethyltetrazolyl-5-thiomethyl group at position 3. Exemplary is the antibacterially effective 7-D-mandelamido-3-(1-carboxymethylthioethyltetrazolyl-5-thiomethyl)-3-ceph em-4-carboxylic acid disodium salt.


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Inventors: Berges, David A. (Wayne, PA, US)

Application Number: 719751
Filing Date: 1976-09-02
Publication_date: 1977-11-08
Assignee: SmithKline Corporation (Philadelphia, PA)
Primary Class(es): 514/204 514/206, 540/226, 540/227
Other Classes:
US Patent Ref:
3989694Nov, 1976Berges260/243.

Other Refs:
Primary Examiner: Rizzo, Nicholas S.
Assistant Examiner:
Attorney: Edgerton; William H.