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Primary Examiner: Friedman, Stanley J.
Assistant Examiner:
Attorney: Smith, Jr.; Arthur A., Santa; Martin M., Cook; Paul J.

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Title: Process for promoting analgesia

Abstract: Analgesia is produced or hyperalgesia is reduced in an animal including human beings by administering 3-(p-trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine either along or with morphine sulfate. A novel composition is provided comprising 3-(p-trifluoromethylphenoxy)-N-methyl-3-phenylpropylamine and 25 to 50 weight percent morphine sulfate based upon the weight of the phenylpropylamine.

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Inventors: Messing, Rita B. (Irvine, CA, US)
Lytle, Loy D. (Concord, MA, US)

Application Number: 683983
Filing Date: 1976-05-06
Publication_date: 1977-07-12
Assignee: Massachusetts Institute of Technology (Cambridge, MA)
Primary Class(es): 514/651
Other Classes:
US Patent Ref:
Other Refs: Other References: terry et al., Fed. Proc., vol. 33, p. 560 (1974).
Fuller et al., Journal of Pharmacology & Experimental Therapeutics, vol. 19, pp. 796-803 (1975).