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Title: Bis-substituted benzyl methanamines

Abstract: Bis-substituted benzyl methanamines, e.g. 1-bis(p-pivaloylbenzyl)methanamine are prepared by hydrolyzing a corresponding N-[bis(p-pivaloylbenzyl)methyl]carbamic acid, alkyl ester and are useful as hypolipidemic agents.


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Inventors: Nadelson, Jeffrey (Lake Parsippany, NJ, US)

Application Number: 642190
Filing Date: 1975-12-18
Publication_date: 1977-07-12
Assignee: Sandoz, Inc. (E. Hanover, NJ)
Primary Class(es): 514/648 549/370, 560/51, 560/54, 564/305
Other Classes:
US Patent Ref:
3689504Sep, 1972Horrom260/570.

Other Refs:
Primary Examiner: Hines, Robert V.
Assistant Examiner:
Attorney: Sharkin; Gerald D., Honor; Robert S., Rothwell; Timothy G.