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Primary Examiner: Daus, Donald G.
Assistant Examiner: Wheeler, David E.
Attorney: Sharkin; Gerald D., Vila; Richard E.

Next ten patents ordered by date:

Esters and amides of pyrimido[4,5-b]quinolin-4(3H)-one-2-carboxylic acids as antiulcer agents
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2-Substituted oxazolo[4,5-b]pyridine anti-inflammatory agents
Compositions containing 7.beta.-alkylthiodeoxynupharadin-6.alpha.-ols
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Use of substituted furan and thiophene carboxaldehydes as hypolipidemic agents

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Title: Bi-4-[1-(quinazolinyl-4)piperidyls] and bis{4-[1-(quinazolinyl-4)piperidyl]alkanes}

Abstract: Disclosed are bi-4-[1-(quinazolinyl-4)piperidyls] and bis{4-[1-(quinazolinyl-4)piperidyl]alkanes}, e.g. 1,3-bis{4-[1-(6,7-dimethylquinazolinyl-4)piperidyl]propane}, having pharmacological activity in animals and useful for example, as anti-obesity and anti-diabetic agents. Said compounds may be prepared by reacting a 4-haloquinazoline with bi-4-piperidyl or a bis(piperidyl-4)alkane.

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Inventors: Simpson, William R. J. (Mendham, NJ, US)

Application Number: 588003
Filing Date: 1975-06-18
Publication_date: 1977-03-08
Assignee: Sandoz, Inc. (E. Hanover, NJ)
Primary Class(es): 514/266.22 514/257, 514/267, 514/866, 514/909, 544/283, 544/284, 544/287, 544/293, 546/186, 549/362
Other Classes:
US Patent Ref:

3931179	Jan, 1976	Simpson	260/256.
3971783	Jul, 1976	Barnish et al.	260/256.

Other Refs: Other References: Tietz, "Clinical Chemistry," pp. 153, 807-808.
White et al., "Principals of Biochemistry," (1968) pp. 974-977.