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Title:
4-Oxo-4H-pyrano[3,2-c]quinoline-2-carboxylic acids and salts thereof
Abstract:
Compounds of the formula ##STR1## wherein R.sub.1 and R.sub.2, which may be identical to or different from each other, are each hydrogen, fluorine, chlorine, alkyl of 1 to 4 carbon atoms, phenyl, hydroxyl, alkoxy of 1 to 3 carbon atoms, alkylmercapto of 1 to 3 carbon atoms, hydroxycarbonyl or ##STR2## where R.sub.3 and R.sub.4 are each alkyl of 1 to 4 carbon atoms or, together with each other and the nitrogen atom to which they are attached, morpholino, piperidino, methylpiperidino or phenyl-piperidino; or R.sub.1 and R.sub.2, together with each other and adjacent carbon atoms of the benzene ring to which they are attached, --CH=CH--CH=CH--, --CH.sub.2 --CH.sub.2 --CH.sub.2 --CH.sub.2 -- or --O--CH.sub.2 --O--; and salts thereof. The compounds are useful as antiallergics.
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Inventors:
Hess, Friedrich Karl (Pointe Fortune, CA, US) Stewart, Patrick Brian (St. Andrews East, CA, US)
Application Number:
615912
Filing Date: 1975-09-23 Publication_date: 1977-03-01 Assignee:
Boehringer Ingelheim GmbH (Ingelheim am Rhein, DT)
Primary Class(es):
514/232.8
514/232.5, 514/285, 514/287, 514/291, 544/80, 544/126, 546/62, 546/65, 546/89, 546/92, 560/9, 560/43
Other Classes:
US Patent Ref:
| 3629290 | Dec, 1971 | Cairns et al. | 260/287. |
Other Refs:
Other References:
Elliott et al., "J. Chem. Soc," 1961 pp. 2796-2800; Chem. Abst. 56:1437i. |