Title: Benzodioxole compounds

Abstract: Benzodioxole compounds of the formula: vasodilator ##STR1## WHEREIN R.sub.1 is hydrogen, lower alkyl, aryl, haloaryl, lower-alkylaryl, lower-alkoxyaryl, methylenedioxyaryl, ethylenedioxyaryl, trifluoromethylaryl, nitroaryl or aminoaryl, R.sub.2 is lower-alkyl, aryl, haloaryl, lower-alkylaryl, lower-alkoxyaryl, methylenedioxyaryl, ethylenedioxyaryl, trifluoromethylaryl, nitroaryl or aminoaryl, or R.sub.1 + r.sub.2 are --(CH.sub.2).sub.4 --, --(CH.sub.2).sub.5 -- or --(CH.sub.2).sub.6 -- and Het is pyridyl, pyrimidinyl, pyridazinyl, pyrazinyl, quinazolinyl, 1,3,5 triazinyl or 1,3-thiazolyl, each being optionally substituted by lower-alkyl, lower-alkoxy, hydroxyl or phenyl. These compounds are used as medicines especially as peripheral vasocilator agent and central nervous system stimulant.

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Inventors: Regnier, Gilbert (Hatenay-Malabry, FR)
Canevari, Roger (Villebon-sur-Yvette, FR)
Laubie, Michel (Vaucresson, FR)
Poignant, Jean-Claude (Bures-sur-Yvette, FR)

Application Number: 562226
Filing Date: 1975-03-26
Publication_date: 1977-03-01
Assignee: Science Union et Cie, Societe Francaise de Recherche Medical (Suresnes, FR)
Primary Class(es): 514/254.02 544/369
Other Classes:
US Patent Ref:

3299067	Jan, 1967	Regnier et al.	260/256.
3585193	Jun, 1971	Regnier et al.	260/268.

Other Refs:
Primary Examiner: Coughlan, Jr., Paul M.
Assistant Examiner:
Attorney: Hueschen; Gordon W.