Title: Phenylvinyl morpholine compounds

Abstract: Morpholine derivatives, typically those of the formula: ##STR1## wherein A is an ethylene or vinylene radical and X is a phenyl radical optionally substituted by one or two substituents selected from halogen atoms, alkyl and alkoxy radicals of 1 to 6 carbon atoms and aryloxy radicals of 1 to 6 carbon atoms, the aryloxy radicals themselves being optionally substituted by one or two substituents selected from halogen atoms and alkyl radicals of 1 to 4 carbon atoms, and the pharmaceutically-acceptable acid-addition salts thereof. Processes for making these compounds, pharmaceutical compositions containing them and a method of restoring to normal abnormal mental states in warm-blooded animals are also disclosed.

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Inventors: McLoughlin, Bernard Joseph (Macclesfield, EN)
Guildford, Allen John (Macclesfield, EN)

Application Number: 567011
Filing Date: 1975-04-10
Publication_date: 1977-03-01
Assignee: Imperial Chemical Industries Limited (London, EN)
Primary Class(es): 514/239.5 544/174, 544/178, 987/366
Other Classes:
US Patent Ref:

2255077

Sep, 1941

Middleton

260/240.

Other Refs:
Primary Examiner: Jiles, Henry R.
Assistant Examiner: Ramsuer, R. W.
Attorney: Cushman, Darby & Cushman