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Primary Examiner: Gotts, Lewis
Assistant Examiner: Suyat, Reginald J.
Attorney: Wenderoth, Lind & Ponack

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Title: Complexes of polysaccharides or derivatives thereof with reduced glutathione and process for preparing said complexes

Abstract: A complex of a polysaccharide or its derivative with reduced glutathione having in its infrared absorption spectrum no absorption peak at about 2500 cm.sup.-.sup.1 which appears in the infrared absorption spectrum of the reduced glutathione. The complex is prepared by reacting the polysaccharide or its derivative activated with an activating agent selected from cyanogen halides, organic cyanic acid esters and alkyl esters of halogenocarbonic acids, with the reduced glutathione at a pH of less than 7. The complex is especially useful for stabilizing thiol groups.

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Inventors: Mizutani, Akihiro (Tenjin, JA)

Application Number: 564212
Filing Date: 1975-04-01
Publication_date: 1977-02-22
Assignee: Meito Sangyo Kabushiki Kaisha (JA)
Primary Class(es): 514/8 530/322
Other Classes:
US Patent Ref:

3619371	Nov, 1971	Crook et al.	260/112.
3645852	Feb, 1972	Axen et al.	260/112.
3679653	Jul, 1972	Schuck et al.	260/112.
3788948	Jan, 1974	Kagedal et al.	260/112.
3882097	May, 1975	Pfister et al.	260/112.

Other Refs: 1,223,281

Feb, 1971	UK.

Other References: Kagedal et al.: Acta Chem. Scan., 25, 1855-1859 (1971).
Dan: Chem. Abst. 68:20005n (1968).