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Primary Examiner: Rose, Shep K.
Assistant Examiner:
Attorney: Sabatine; Paul L., Ciotti; Thomas E., Mandell; Edward L.

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Title: Ophthalmological bioerodible drug dispensing formulation

Abstract: An ophthalmological bioerodible dosage form for ophthalmic drugs is disclosed. The dosage form comprises particles 10 to 300 microns made of drug dispersed within a drug release rate controlling material which bioerodes in the environment of the eye.


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Inventors: Shell, John W. (Los Altos, CA, US)

Application Number: 592555
Filing Date: 1975-07-02
Publication_date: 1977-01-04
Assignee: Alza Corporation (Palo Alto, CA)
Primary Class(es): 424/438 424/497
Other Classes:
US Patent Ref:
2671750Mar, 1954Macek424/243.
2828319Mar, 1958Magerlein et al.424/243.
2861920Nov, 1958Dale et al.424/80.
2897120Jul, 1959Cronin et al.424/80.
3062712Nov, 1962Dale et al.424/80.
3755558Aug, 1973Scribner424/47.
3773919Nov, 1973Boswell et al.424/19.
3826258Jul, 1974Abraham128/260.
3867519Feb, 1975Michaels424/19.
3887699Jun, 1975Yolles424/19.
3914402Oct, 1975Shell424/32.

Other Refs: Other References: Speiser Chem. Abst., 67, No. 14813n (1967) "Ophthalmic Dispersions and Preparations", Abst. of Farmaco., Ed. Pract., 22(4):181-209 (1967).(FR).