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Title:
Ophthalmological bioerodible drug dispensing formulation
Abstract:
An ophthalmological bioerodible dosage form for ophthalmic drugs is disclosed. The dosage form comprises particles 10 to 300 microns made of drug dispersed within a drug release rate controlling material which bioerodes in the environment of the eye.
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Inventors:
Shell, John W. (Los Altos, CA, US)
Application Number:
592555
Filing Date: 1975-07-02 Publication_date: 1977-01-04 Assignee:
Alza Corporation (Palo Alto, CA)
Primary Class(es):
424/438
424/497
Other Classes:
US Patent Ref:
| 2671750 | Mar, 1954 | Macek | 424/243. | | 2828319 | Mar, 1958 | Magerlein et al. | 424/243. | | 2861920 | Nov, 1958 | Dale et al. | 424/80. | | 2897120 | Jul, 1959 | Cronin et al. | 424/80. | | 3062712 | Nov, 1962 | Dale et al. | 424/80. | | 3755558 | Aug, 1973 | Scribner | 424/47. | | 3773919 | Nov, 1973 | Boswell et al. | 424/19. | | 3826258 | Jul, 1974 | Abraham | 128/260. | | 3867519 | Feb, 1975 | Michaels | 424/19. | | 3887699 | Jun, 1975 | Yolles | 424/19. | | 3914402 | Oct, 1975 | Shell | 424/32. |
Other Refs:
Other References:
Speiser Chem. Abst., 67, No. 14813n (1967) "Ophthalmic Dispersions and Preparations", Abst. of Farmaco., Ed. Pract., 22(4):181-209 (1967).(FR). |