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N.sup.6 -Substituted-9-[3-(4-phenyl-piperazino)-propyl]-adenines 2-[[4-(2,3-Dihydro-2-oxo-1H-benzimidazol-1-yl)-1-(piperidinyl or 1,2,3,6-tetrahydro-1-pyridinyl)]alkyl]-1H-benz[de]isoquinoline-1,3(2H)-d iones 2-[(4-Oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8- yl)alkyl]-1H-benz[de]isoquinolin-1,3(2H)-diones 9-Xanthylamin oalkylpyridine derivatives Pharmaceutical tablet N,N-dimethyl-O-[1-methyl-3-N-methylcarbaminyl-methyl-pyrazo l(5)yl]-carbamic acid ester Anthelmintically active 2-carbalkoxyamino-5(6)-phenyl sulfonyloxy benzimidazoles Anthelmintically active 2-carbalkoxyamino benzimidazolyl-5(6)-sulfonic acid phenyl esters Antagonism of ethanol intoxication with 4[(4,5-dihydro-2-1H-imidazolyl)methoxy]-N,N,2-trimethylbenzenamine Optionally substituted 3-methylsulfinyl indazoles
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Title:
Piperazine compounds
Abstract:
Cardioactive 3-methyl-3-(3,4-dialkoxybenzyl)-piperazine compounds of the formula ##STR1## and their salts with physiologically tolerable acids; methods for making the same; pharmaceutical compositions containing the compounds as an active ingredient; and methods of treating cardiac diseases such as arrhythmia with said compounds.
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Inventors:
Cyrus, Richard (Ludwigshafen (Rhine), DT) Raschack, Manfred (Weisenheim am Sand, DT)
Application Number:
600870
Filing Date: 1975-07-31 Publication_date: 1976-12-07 Assignee:
Knoll A.G. Chemische Fabriken (Ludwigshafen, DT)
Primary Class(es):
514/255.04
514/821, 544/384, 544/396, 544/398
Other Classes:
US Patent Ref:
| 2997473 | Aug, 1961 | de Jongh et al. | 260/268. |
Other Refs:
Primary Examiner:
Daus, Donald G.
Assistant Examiner:
Tovar, Jose
Attorney:
Bentz; Donald R.
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