Title: Microporous drug delivery device

Abstract: A drug delivery device for administering a drug at a controlled rate for a prolonged period of time to produce a local or systemic physiological or pharmacological effect is comprised of a wall surrounding a reservoir containing a drug. The reservoir is formed of a solid drug carrier permeable to the passage of the drug. The wall is formed in at least a part of a microporous material the pores of which contain a drug release rate controlling medium also permeable to the passage of the drug, but the rate of passage of the drug through the medium is lower than the rate passage of the drug through the solid drug carrier so that drug release by the medium in the microporous wall is the drug release rate controlling step for releasing drug from the drug delivery device.

Do you think this is a good invention? Vote now:

Votes so far: For:(0) Against:(0)
Other info:

Inventors: Zaffaroni, Alejandro (Atherton, CA, US)

Application Number: 623427
Filing Date: 1975-10-17
Publication_date: 1976-11-23
Assignee: Alza Corporation (Palo Alto, CA)
Primary Class(es): 424/430 128/833, 424/423, 424/424, 424/432, 424/433, 424/434, 424/435, 424/436, 424/473
Other Classes:
US Patent Ref:

3490454	Jan, 1970	Goldfarb et al.	128/260.
3598122	Aug, 1971	Zaffaroni	128/268.
3705938	Dec, 1972	Hyman et al.	424/19.
3710795	Jan, 1973	Higuchi et al.	128/260.
3896819	Jul, 1975	Zaffaroni	128/130.
3921636	Nov, 1975	Zaffaroni	128/260.
3948254	Apr, 1976	Zaffaroni	128/260.

Other Refs:
Primary Examiner: Medbery, Aldrich F.
Assistant Examiner:
Attorney: Sabatine; Paul L., Mandell; Edward L., Ciotti; Thomas E.