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Title:
4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine-N-oxide isomer
Abstract:
A specified geometrical isomer of 4-(5H-dibenzo-[a,d]cyclohepten-5-ylidene)-1-methylpiperidine-N-oxide is disclosed to have pharmaceutical utility as an appetite stimulant. Also disclosed are processes for the preparation of such compound; pharmaceutical compositions comprising such compound; and methods of treatment comprising administering such compound and compositions.
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Inventors:
Christy, Marcia E. (Perkasie, PA, US)
Application Number:
525324
Filing Date: 1974-11-20 Publication_date: 1976-11-16 Assignee:
Merck & Co., Inc. (Rahway, NJ)
Primary Class(es):
514/325
546/203
Other Classes:
US Patent Ref:
Other Refs:
Other References:
Ebnother et al., Helv. Chim. Acta 1965, vol. 48, pp. 1237-1249. Winthrop et al., J. Org. Chem. 1962, vol. 27, pp. 230-240. Ishwariah Chem. Abst. 1970, vol. 72, No. 39328z. Mertz et al., Chem. Abst. 1970, vol. 72, No. 20541s. Nakayama et al., Chem. Abst. 1973, vol. 78, 97494k. Vignoli et al., Chem. Abst. 1966, vol. 65, Col. 16793. |