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Primary Examiner: Trousof, Natalie
Assistant Examiner:
Attorney: Westlake, Jr.; Harry E., Arno; James A., Nicholson; William H.

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Title: 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-methylpiperidine-N-oxide isomer

Abstract: A specified geometrical isomer of 4-(5H-dibenzo-[a,d]cyclohepten-5-ylidene)-1-methylpiperidine-N-oxide is disclosed to have pharmaceutical utility as an appetite stimulant. Also disclosed are processes for the preparation of such compound; pharmaceutical compositions comprising such compound; and methods of treatment comprising administering such compound and compositions.


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Inventors: Christy, Marcia E. (Perkasie, PA, US)

Application Number: 525324
Filing Date: 1974-11-20
Publication_date: 1976-11-16
Assignee: Merck & Co., Inc. (Rahway, NJ)
Primary Class(es): 514/325 546/203
Other Classes:
US Patent Ref:
3014911Dec, 1961Engelhardt260/293.
3642808Feb, 1972Schroter et al.260/293.
3851059Nov, 1974Prugh424/267.

Other Refs: Other References: Ebnother et al., Helv. Chim. Acta 1965, vol. 48, pp. 1237-1249.
Winthrop et al., J. Org. Chem. 1962, vol. 27, pp. 230-240.
Ishwariah Chem. Abst. 1970, vol. 72, No. 39328z.
Mertz et al., Chem. Abst. 1970, vol. 72, No. 20541s.
Nakayama et al., Chem. Abst. 1973, vol. 78, 97494k.
Vignoli et al., Chem. Abst. 1966, vol. 65, Col. 16793.