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Primary Examiner: Drezin, Norman A.
Assistant Examiner:
Attorney: Voet; Martin A.

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Title: Vehicle composition containing 1-substituted azacycloheptan-2-ones

Abstract: There is disclosed an improved method for topically administering a physiologically active agent to a human or animal by dissolving an effective amount of the agent in a carrier containing suitable amounts of 1-substituted-azacycloheptan-2-one, as defined herein, and contacting the skin or other membranes of the human or animal with the resulting composition, whereby penetration of the skin or membranes is enhanced.

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Inventors: Rajadhyaksha, Vithal Jagannath (Mission Viejo, CA, US)

Application Number: 588247
Filing Date: 1975-06-19
Publication_date: 1976-11-02
Assignee: Nelson Research & Development Company (Irvine, CA)
Primary Class(es): 424/60 424/59, 424/275.1, 424/278.1, 514/24, 514/29, 514/50, 514/269
Other Classes:
US Patent Ref:

3551554	Dec, 1970	Herschler	424/274.
3891757	Jun, 1975	Higuchi	424/274.

Other Refs: Other References: Laden, Chemical Abstracts 73:102083d, (1970).
Anton'ev, et al., Chemical Abstracts 75:24868p, (1971).
Wehner, et al., Chemical Abstracts 74:87436w, (1971).